Calendar Details

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Monday, March 04

Advancing High-Throughput Biology:
Data-Driven Science and Science-Driven Data

Karin Remington, Arjuna Solutions, Washington, DC
Special Joint Institute for Biological Sciences–
Joint Institute for Computational Sciences (JICS)
Joint Seminar in Informational Biology
9:00 AM — 10:00 AM, Building 4500-N, Weinberg Auditorium
Contact: Gary Sayler (saylergs@ornl.gov), 865,241.1244

Abstract

The goal of acquiring the sequence of the entire human genome had been held up as the "moon-shot" for biology, and it inspired the imaginations of scientists for decades. Using lessons learned from the human genome project, we now have access to genome sequences for countless species, and detailed meta-genomic sequences from a wide variety of experimental environments, from extreme communities living on the edge in oceanic heat vents and arctic ice, to the communities living within and around each of us every day. Genomic science is just one example of where data collection is far outstripping our analytic abilities. How can we structure our labs, projects, programs and proposals to inspire the imagination of the next generation in biological science?

About the Speaker:
Dr. Remington has a Ph.D. in mathematics from the University of Kentucky, and was Householder Fellow of Scientific Computing at ORNL from 1992 to 1994. She joined the "Assembly Team" at Celera Genomics in 1999. This group established the scalability of the "whole-genome-shotgun" approach to genome sequencing by assembling first the fruit fly genome (Science, 2000) and then the human genome (Science, 2001). She joined the nascent J.Craig Venter Institute in 2002, and led the informatics group there through the draft-sequencing and comparative analysis of the dog genome (Science, 2003), the metagenomic analysis of the Sargasso Sea (Science, 2004), and its successor, the Global Ocean Sampling project (PLoS Biology, 2007). In 2007, Remington joined the NIH, as Director of the Center for Bioinformatics and Computational Biology in the National Institute of General Medical Sciences. In that role, she was chair of the NIH's Biomedical Information Science and Technology Initiative (BISTI) consortium, and co-chair of the federal government's interagency "Big Data Initiative", which was formed in 2011 and released its first major funding initiative in less than a year with a White House announcement in March 2012. She recently left NIH to become partner and Chief Technology and Science Officer of a start-up company based on proprietary technology and software for business analytics.