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DOE Human Genome Program Contractor-Grantee Workshop VI

November 9-13, 1997, Santa Fe, NM

The electronic form of this document may be cited in the following style:
Human Genome Program, U.S. Department of Energy, DOE Human Genome Program Contractor-Grantee Workshop VI, 1997.

Welcome to the Sixth Contractor-Grantee Workshop sponsored by the Department of Energy (DOE) Human Genome Program (HGP). This workshop provides a unique opportunity for HGP investigators to discuss and share the successes, problems, and challenges of their research as well as new material resources and software capabilities. The meeting also gives genome scientists and administrative staff an overview of the program's progress and content, a chance to assess the impact of new technologies, and, perhaps most important, a forum for initiating new collaborations. We hope you will take advantage of opportunities offered by this meeting and by the always-beautiful surroundings in Santa Fe. 

The 158 abstracts in this booklet describe the most recent activities and accomplishments of grantees and contractors funded by DOE's human and microbial genome programs, as well as the research of a few invited guests. All projects will be represented at the poster sessions, so you will have an opportunity to meet with researchers. Plenary sessions will be held at the Eldorado Hotel and poster sessions at the La Fonda Hotel. New informatics resources also will be demonstrated during the poster sessions. 

The main challenge facing the genome program today is high-throughput sequencing. DOE is addressing this challenge with the formation of the Joint Genome Institute (JGI) under the direction of Elbert Branscomb. JGI will take advantage of the complementary strengths of DOE's three largest genome programs and those at other laboratories and universities to make more efficient and effective use of diverse expertise and resources. A major step in JGI's inauguration is the creation of a DNA sequencing factory in Walnut Creek, California, located halfway between the Lawrence Berkeley and Lawrence Livermore National Laboratories. Factory output will be high-accuracy human DNA sequences that will be deposited into public databases in accordance with "Bermuda principles." 

The U.S. Human Genome Project is nearing the end of its second 5-year plan, which was produced in 1993 by DOE and the National Institutes of Health following rapid progress toward the goals of the original 5-year plan of 1990. We look forward to defining and meeting the goals of the project's next 5 years, now being developed with input from the broad genome scientific community. Although many challenges lie ahead, we are optimistic about the success of this grand project and await its many contributions to science and society. 

We anticipate a very interesting and productive meeting and offer our sincere thanks to all the organizers and to you, the scientists whose vision and efforts have realized the promise of the genome program. 

Sincerely, 
Ari Patrinos 
Associate Director 
Office of Biological and Environmental Research 
U.S. Department of Energy 


Date Published: October 1997
Prepared for the
U.S. Department of Energy
Office of Energy Research
Office of Biological and Environmental Research
Washington, D.C. 20585
under budget and reporting code KP 0404000

Prepared by
Human Genome Management Information System
Oak Ridge National Laboratory
Oak Ridge, TN 37830-6480 
Managed by
LOCKHEED MARTIN ENERGY RESEARCH CORP.
for the
U.S. DEPARTMENT OF ENERGY
UNDER CONTRACT DE-AC05-96OR22464 

Human Genome Project 1990–2003

The Human Genome Project (HGP) was an international 13-year effort, 1990 to 2003. Primary goals were to discover the complete set of human genes and make them accessible for further biological study, and determine the complete sequence of DNA bases in the human genome. See Timeline for more HGP history.

Human Genome News

Published from 1989 until 2002, this newsletter facilitated HGP communication, helped prevent duplication of research effort, and informed persons interested in genome research.