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In this issue...
Genome Project
In the News
Microbial Genomics
Ethical, Legal, and Social Issues and Educational Resources
Proteomics
Genetics in Medicine
Informatics
Web, Other Resources, Publications
Funding
Meeting Calendars & Acronyms
BAC End Sequencing Extends Contigs. Software tools are helping to position STCs. One tool, provided by the Genome Channel [http://compbio.ornl.gov/tools/channel/]>, allows investigators to view the contig positions of more than 15,000 BAC end sequences and their relationships to other clones and predicted genes and exons (gene-coding regions). In the figure, the black bar represents 250kb of a much longer contig. Below the bar, the long horizontal lines denote BAC clones, of which the first, fifth, and sixth are candidates for extending the seed contig to the left. Above the bar, vertical tick marks indicate exons as predicted by GRAIL software. Exons connected by short horizontal lines represent putative gene models for the contig's forward DNA strand.
[Figure contributed by Richard Mural, Morey Parang, and Manesh Shaw]
The electronic form of the newsletter may be cited in the following style:
Human Genome Program, U.S. Department of Energy, Human Genome News (v10n1-2).
The Human Genome Project (HGP) was an international 13-year effort, 1990 to 2003. Primary goals were to discover the complete set of human genes and make them accessible for further biological study, and determine the complete sequence of DNA bases in the human genome. See Timeline for more HGP history.
Published from 1989 until 2002, this newsletter facilitated HGP communication, helped prevent duplication of research effort, and informed persons interested in genome research.