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Human Genome News Archive Edition

Human Genome News, May 1991; 3(1)

Genome Literature Abstracts

As time and space permit, Human Genome News will publish information about selected new books and journals that may be of interest to our readers. This is not a comprehensive list, and announcements will be taken from material at hand. We welcome news from authors and publishers about new and upcoming publications.


Genome Analysis, a new series of books on genome structure and function, reviews some of the latest findings, methods, and ideas in human and animal genetics. Edited by Kay Davies (University of Oxford) and Shirley Tilghman (Princeton University) and published every 4 to 6 months, each volume focuses on one broad theme. Volume I, Genetic and Physical Mapping is now available; forthcoming titles include Gene Expression and Its Control and Genes and Phenotypes. $40 per volume. [Cold Spring Harbor Laboratory; Fulfillment Department, LM90; 10 Skyline Drive; Plainview, NY 11803-9729; United States, except New York State: 800/843-4388; all other locations: 516/367-8423; Fax: 516/367-8432.]

Molecular Cloning: A Laboratory Manual (Second Edition) has tripled in size and grown to three volumes since it was first published in 1982. The 1989 manual describes not only manipulations of recombinant DNA, but also the reasons for particular steps and the principles underlying the methodology. Three-volume set, plastic comb binding, $115. One-volume, clothbound reference edition, $225. [Cold Spring Harbor Laboratory (see entry above).]

Genes and Genomes by Maxine Singer (Carnegie Institution of Washington) and Paul Berg (The Beckman Center for Molecular and Genetic Medicine, Stanford University) was written to capture the sense of discovery, understanding, and anticipation that has followed the recombinant DNA breakthrough. Part I reviews the field of molecular genetics in the early 1970s; Part II examines the logic, concepts, and general practices of gene cloning and the characterization and manipulation of DNA; Part III presents the major take-home messages of the new experimental paradigm; Part IV introduces the upcoming companion Volume II, a sampling of case studies of genetic systems that have been especially illuminated by the recombinant DNA approach. Over 700 illustrations are included. Casebound with jacket, $52. [Marketing Director, University Science Books; 20 Edgehill Road; Mill Valley, CA 94941.]

DNA Science: A First Course in Recombinant DNA Technology by David A. Micklos (Cold Spring Harbor Laboratory) and Greg A. Freyer (Columbia University) is a laboratory text that introduces the theory, practice, and applications of recombinant DNA technology. Written in a semijournalistic style and designed to be read from cover to cover, the book presupposes no prior experience by student or instructor. Paper, $29.95. [Published by Cold Spring Harbor Laboratory Press and Carolina Biological Supply Company (CBSC). Order from CBSC, 2700 York Road; Burlington, NC 27215; 919/584-0381 or 800/334-5551; North Carolina only: 800/632-1231].

Genetic Monitoring and Screening in the Workplace, an Office of Technology Assessment (OTA) report, resulted from a 1989 OTA survey of some 2000 companies and unions to determine which of them used genetic monitoring or screening tests of workers or job applicants. The report discusses the survey, ethical and legal concerns, and two central policy issues identified by OTA: (1) the federal government's role in the regulation, oversight, or promotion of genetic monitoring and screening tests and (2) the adequacy of federally sponsored research on the relationships between genes and the environment. Full report (052-003-01217-1), $12. [Superintendent of Documents; U.S. Government Printing Office; Washington, DC 20402-9325; 202/783-3238.] Report summaries, free. [OTA, U.S. Congress; Washington, DC 20510-8025; 202/224-8996.]

Human Gene Mapping Techniques by Helen Donis-Keller (Washington University School of Medicine) is a step-by-step guide to designing a mapping project, identifying a gene's chromosomal location, developing high-resolution physical and genetic maps, and cloning the gene. With a major emphasis on genetic linkage mapping, this book presents gene-mapping strategies for researchers who have some experience with molecular biology and gene-cloning techniques. 1990. $39.95. [Stockton Press; 15 East 26th Street; New York, NY 10010; United States, except New York: 800/221-2123; New York: 212/481-1334; Fax: 212/779-9479.]


HGMIS Staff

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Human Genome Program, U.S. Department of Energy, Human Genome News (v3n1).

Human Genome Project 1990–2003

The Human Genome Project (HGP) was an international 13-year effort, 1990 to 2003. Primary goals were to discover the complete set of human genes and make them accessible for further biological study, and determine the complete sequence of DNA bases in the human genome. See Timeline for more HGP history.

Human Genome News

Published from 1989 until 2002, this newsletter facilitated HGP communication, helped prevent duplication of research effort, and informed persons interested in genome research.