Sponsored by the U.S. Department of Energy Human Genome Program
Human Genome News Archive Edition
Human Genome News, September 1992; 4(3)
The tenth edition of the book Mendelian Inheritance in Man: Catalogs of Autosomal Dominant, Autosomal Recessive, and X-Linked Phenotypes, by Victor A. McKusick, Clair A. Francomano, and Sylianos Antonarakis [all at Johns Hopkins University (JHU) School of Medicine], was published this year. Incorporating information through March 1, the two volumes contain 5710 entries (869 more than the ninth edition in 1990); the first edition of the catalog, published in 1966, contained 1487 entries. The genetic code is presented in two alternative formats, and many more entries now list allelic variants. 2320 pp, $150. (JHU Press; 701 West 40th Street, Suite 275; Baltimore, MD 21211-2190; 800/537-5487 or 410/516-6960, Fax: 410-516-6998.)
Mendelian Inheritance in Man (MIM) is also available as OMIM-a full-text online database located at JHU. OMIM entries, which are arranged according to single-gene disorder, may include clinical observations, inheritance patterns, references, allelic variants, chromosomal location, defective gene products, and linkage information. Updated daily, the database serves both the clinical and laboratory communities by providing information helpful in differential diagnosis, genetic counseling, biochemical defect identification, and linkage studies. Searchers can locate relevant material in OMIM and then use the MIM number or chromosomal location for cross-referencing with Genome Data Base (GDB). Revision bars ("") in OMIM reflect material added to the database after the book was printed. [For more information on the database, see HGN 3(4), 1-6, (November 1991).]
To become a registered GDB/OMIM user, contact one of the User Support offices listed in the GDB Forum.
The electronic form of the newsletter may be cited in the following style:
Human Genome Program, U.S. Department of Energy, Human Genome News (v4n3).
The Human Genome Project (HGP) was an international 13-year effort, 1990 to 2003. Primary goals were to discover the complete set of human genes and make them accessible for further biological study, and determine the complete sequence of DNA bases in the human genome. See Timeline for more HGP history.
Published from 1989 until 2002, this newsletter facilitated HGP communication, helped prevent duplication of research effort, and informed persons interested in genome research.