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1990–2003

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Human Genome News, March 1993; 4(6)

GENOME CENTER:

University of California, Berkeley

Drosophila Genome Center
(NIH; established 1992)

DIRECTOR:
Gerald M. Rubin

CONTACT:
Gerald M. Rubin
(HHMI, UCB, 510/643-9945, Fax: -9947)
539 LSA Bldg.
University of California
Berkeley, CA 94720

OTHER KEY RESEARCHERS:
Daniel L. Hartl (Harvard University), Christopher H. Martin (LBL), Michael J. Palazzolo (LBL), Allan C. Spradling (Carnegie Institute of Washington, HHMI)

MAJOR GOALS:

  • Generation of a physical map of the Drosophila melanogaster genome at about 20-kb resolution by STS-content mapping of a P1 library.
  • Integration into the physical map of sites of high biological interest, including known genes, cDNAs, and lethal P-element insertion sites.

MAJOR ACCOMPLISHMENTS:

  • Preparation of robotically arrayed 10,000-member bacteriophage P1 library for automated screening and contig assembly.
  • Construction of a map (by in situ hybridization against polytene chromosomes) for nearly 1500 P1 clones that will be starting points for contig assembly.
  • Construction of a map (by in situ hybridization) for several hundred P-element insertion sites.

AVAILABLE RESOURCES:

  • Mapped P1 clones.
  • Drosophila strains with mapped single P-element insertions will be deposited in the NSF-funded Indiana Drosophila Stock Center for distribution.
  • Adaptation of the C. elegans database, for management and graphical display of Drosophila data.

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The electronic form of the newsletter may be cited in the following style:
Human Genome Program, U.S. Department of Energy, Human Genome News (v4n6).

Human Genome Project 1990–2003

The Human Genome Project (HGP) was an international 13-year effort, 1990 to 2003. Primary goals were to discover the complete set of human genes and make them accessible for further biological study, and determine the complete sequence of DNA bases in the human genome. See Timeline for more HGP history.

Human Genome News

Published from 1989 until 2002, this newsletter facilitated HGP communication, helped prevent duplication of research effort, and informed persons interested in genome research.