Sponsored by the U.S. Department of Energy Human Genome Program
Human Genome News Archive Edition
Human Genome News, April-June 1996; 7(6)
Human Genome Project researchers reached the project's large-scale genetic-mapping goals with the publication of two maps in the March 14, 1996, issue of Nature: a dense genetic map of the laboratory mouse constructed by Eric Lander and colleagues at Whitehead Institute-MIT and a separate linkage map of the human genome by Jean Weissenbach's group at Généthon.
The mouse map [http://www.broad.mit.edu/] contains 7377 markers scattered along 20 pairs of chromosomes, or about 1 every 400,000 nucleotide bases. The human genetic map is composed entirely of 5264 microsatellite markers (1 every 0.7 cM) that can be assayed rapidly in large numbers by PCR.
With genetic maps for both human and mouse now essentially complete, the second phase of the Human Genome Project is concentrating on sequence-ready map production and large-scale sequencing projects.
The electronic form of the newsletter may be cited in the following style:
Human Genome Program, U.S. Department of Energy, Human Genome News (v7n6).
The Human Genome Project (HGP) was an international 13-year effort, 1990 to 2003. Primary goals were to discover the complete set of human genes and make them accessible for further biological study, and determine the complete sequence of DNA bases in the human genome. See Timeline for more HGP history.
Published from 1989 until 2002, this newsletter facilitated HGP communication, helped prevent duplication of research effort, and informed persons interested in genome research.