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Human Genome News Archive Edition

Human Genome News, January-June 1997; 8:(3-4)

Homologs of Human Disease Genes Found in Model Organisms

Researchers at the National Center for Biotechnology Information (NCBI) used known DNA sequences of 70 human genes linked to such disorders as colon cancer and obesity to search public sequence databases for counterparts in yeast, bacteria, and roundworm. They found the highest number of matches in worm databases (36%) and expect to find more as the other half of the worm’s genes are sequenced. Another 10% to 20% of the human genes had counterparts inbacteria and yeast. New functions were predicted for a number of disease genes. A paper reporting this work by Eugene Koonin and colleagues (NCBI) is published in Proc. Natl. Acad. Sci. USA 94, 5831-36 (May 1997).



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Human Genome Program, U.S. Department of Energy, Human Genome News (v8n3).

Human Genome Project 1990–2003

The Human Genome Project (HGP) was an international 13-year effort, 1990 to 2003. Primary goals were to discover the complete set of human genes and make them accessible for further biological study, and determine the complete sequence of DNA bases in the human genome. See Timeline for more HGP history.

Human Genome News

Published from 1989 until 2002, this newsletter facilitated HGP communication, helped prevent duplication of research effort, and informed persons interested in genome research.