Beyond the Identification of Transcribed Sequences:
Functional, Evolutionary and Expression Analysis
12th International Workshop
October 25-28, 2002
Washington, DC


List of Abstracts * Speakers * Organizers * Authors * Original Announcement


The German cDNA Network:  cDNAs for Functional Genomics and Proteomics

Ruth Wellenreuther1, Stephanie Bechtel1, Petra Moosmayer1, Regina Albert1, Ingo Schupp1, Vladimir Kuryshev1, Detlev Bannasch1, Dorit Arlt1, Ulrike Korf1, Rainer Pepperkok2, Jeremy Simpson2, Annemarie Poustka1, Stefan Wiemann1, and the German cDNA Consortium
1 Molecular Genome Analysis, German Cancer Research Center, Im Neuenheimer Feld 506, D-69120 Heidelberg, Germany and 2 Cell Biology Program, European Molecular Biology Laboratory, Meyerhofstrasse 1, D-69117 Heidelberg, Germany
Telephone: ++49 6221 56 4765
Fax: ++49 6221 56 4782
Email: r.wellenreuther@dkfz.de

We have formed a network within the German Genome Project aiming at the generation and sequencing of novel full-length cDNAs, and the comprehensive functional analysis of the encoded proteins. Over 6,200 cDNAs (covering >18 Mb) have been sequenced since. This set and greater 140,000 EST-sequenced clones is used to generate a minimal set of full-length cDNAs for use in subsequent functional analysis. In order to study the function of proteins within complex biological systems like cell cycle regulation, apoptosis, or protein secretion, a multitude of complementary approaches need to be followed that combine genomics and proteomics strategies, but also cell biology and computational biology. The availability of full-length cDNAs is elementary for most of these. Only the integration of data from many sources will help to eventually understand protein function and interaction in protein networks and complex biological systems.



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List of Abstracts * Speakers * Organizers * Authors * Original Announcement


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