TRANSCRIPTOME 2002: From Functional Genomics to Systems
Systems Biology: Integrating Genomics, Proteomics, Computation and Biology
Leroy Hood, Institute for Systems Biology, Seattle, WA
The Human Genome Project has altered the view and practice of biology and has led to several paradigm changes—systems biology, and predictive and preventive medicine. I will discuss these changes and consider the analysis of two biological systems: galactose metabolism in yeast, and sea urchin development, using integrative systems approaches. I will also discuss the Institute for Systems Biology and the approaches we are taking to create an optimal environment for carrying out systems biology.
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