TRANSCRIPTOME 2002: From Functional Genomics to Systems
New Cancer Genome Anatomy Project (CGAP) Internet Resource for the Research Community
Lynette H. Grouse, Carl F. Schaefer, Susan F. Greenhut, Kenneth H. Buetow and Robert L. Strausberg, National Cancer Institute, National Institutes of Health, Bethesda, MD
The Cancer Genome Anatomy Project is a collaborative project launched by the National Cancer Institute in 1997. This Project is an interdisciplinary initiative to build a comprehensive information infrastructure for profiling molecular changes in cells associated with cancer. Critical to deciphering the molecular profiles of cancer cells is the availability of both a robust molecular database and analysis tools. The goal of such a database is to facilitate the seamless integration of molecular and clinical data. The new CGAP interface (http://cgap.nci.nih.gov/) supports a variety of molecular analysis tools that allow flexible retrieval and analysis of data. Data is accessed through new entry points that provide analysis of the data from specific molecular or biological viewpoints, such as Genes, Chromosomes, Tissues, or Pathways. Data for both human and mouse tissues is included in the database. In summary, the new CGAP Internet resource provides a comprehensive database and informatics tools that will assist both basic and clinical investigators in defining and characterizing the molecular profiles of cancer cells, with anticipated applications in all areas of cancer research.
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