Sponsored by the U.S. Department of Energy Human Genome Program
Human Genome News, Nov. 1994; 6(4):10
University of Texas Health Science Center at San Antonio
- UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO (UTHSCSA)
- (NIH, established 1992)
- SUSAN L. NAYLOR, Director
- CONTACT: Naylor (210/567-3842, Fax: -6781, firstname.lastname@example.org); UTHSCSA; 7703 Floyd Curl Drive; San Antonio, TX 78284-7762.
- OTHER KEY RESEARCHERS
- Peter Cartwright (Univ. of Utah)
- David Housman (Massachusetts Institute of Technology)
- Robin Leach
- Peter O'Connell
- Stephanie Sherman (Emory Univ.)
- Brad Windle
- Construction of radiation hybrid, genetic linkage, and contig maps for human chromosome 3.
- Development of 2500 sequence tagged sites at 100-kb intervals on chromosome 3.
- Development of a chromosome 3-specific database (with the Univ. of Utah genome center).
- Production of framework hybrids that divide chromosome 3 into 23 regions.
- Construction of genetic linkage maps (one with 120 SSRs and 52 markers and another with 198 dinucleotide repeats) and a radiation hybrid map with 150 loci.
- Yeast artificial chromosome contigs covering over 80% of chromosome 3. Database contains 20,000 yeast artificial chromosome X sequence tagged site and YACx probe records.
- Characterization of 450 simple repeat polymorphisms for chromosome 3.
- Design and assembly of polymerase chain reaction primers for 81 genes and RFLPs.
- Development of a semiautomated system for polymerase chain reaction reactions and automated gel loading robotics for both Centre d'Etude du Polymorphisme Humain screening and radiation hybrids.
- Framework hybrids for chromosome 3. Polymerase chain reaction primers for polymorphic dinucleotide repeats and genes mapping to chromosome 3.
- Scheme for automating Centre d'Etude du Polymorphisme Humain typing.
- Chromosome 3-specific database.
- Pre- and postdoctoral training in human genome research.
- Yeast artificial chromosome clones, chromosome 3 cosmid library, P1 screening.
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The electronic form of the newsletter may be cited in the following style:
Human Genome Program, U.S. Department of Energy, Human Genome News (v6n4).