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Human Genome News Archive Edition
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  Vol.10, No.1-2   February 1999

In this issue...

Available in PDF

Genome Project

In the News

Microbial Genomics

Ethical, Legal, and Social Issues and Educational Resources


Genetics in Medicine


Web, Other Resources, Publications


Meeting Calendars & Acronyms

  • Genome and Biotechnology Meetings
  • Training Courses and Workshops
  • Acronyms

HGN archives and subscriptions

Human Genome Project Information home

Microbial Genomics News

Unfinished Microbial Genomes Searchable

The National Center for Biotechnology Information (NCBI) Web site links to sequences from unfinished microbial genomes for BLAST searching. These unfinished sequences, which are not yet in GenBank nor accessible via Entrez, also can be retrieved from their associated sequencing centers by ftp or Web. The 18 finished microbial genomes are searchable by Entrez via the NCBI site.

TIGR Releases Chlorobium tepidum Sequence

In September 1998, The Institute for Genomic Research (TIGR) announced the release of more than 1.9 Mb of genome sequence from Chlorobium tepidum, a photosynthetic gram-negative bacterium. The TIGR program, supported by DOE, has reached 3 coverage in the random-sequencing phase. The photosynthetic C. tepidum may play an important role in the earth's overall cycle of carbon use.

Microbial Genome Newsgroup

Microbial-Genomes is a newsgroup for the discussion of microbial (bacterial, archaeal, and small eukaryotic) genomes. To subscribe, email microdomo@mds.qmw.ac.uk, and send the command subscribe microbial-genomes as the only text in the body of a message.

M. jannaschii Paper Still Hot

The May-June 1998 issue of ScienceWatch, a publication of the Philadelphia-based Institute for Scientific Information, noted that the paper describing the complete genomic sequence of the 1.7-Mb archaeon Methanococcus jannaschii was the fifth most-cited paper in biology for the first 2 months of 1998. The paper, by C.J. Bult and others at The Institute for Genomic Research, confirmed the existence of a third kingdom of life on earth when it appeared in 1996 in Science (273, 1058). At the time of publication, only about one-third of the 1700 genes in M. jannaschii were found to resemble known genes, and the other two-thirds were completely novel to biology. This research was supported by the DOE Microbial Genome Program.

Microbial Information Broker Includes 18

The Genome Information Broker (GIB) now includes 18 microbial genomes that have been sequenced completely and released from DDBJ, EMBL, and GenBank databases. GIB information includes the numbers and names of clones, open reading frames and genes, and sequences. Results are represented in interactive graphics and tables.

UIUC Web Sites Include Microbial Information

Web sites at the University of Illinois at Urbana-Champaign present

  • Sequenced and incomplete genomes, including microbial, found in public databases, with links to sequencing institution, functional overview, publication, and further information.
  • Continuous annotations of Methanococcus jannaschii functions

The electronic form of the newsletter may be cited in the following style:
Human Genome Program, U.S. Department of Energy, Human Genome News (v10n1-2).

Human Genome Project 1990–2003

The Human Genome Project (HGP) was an international 13-year effort, 1990 to 2003. Primary goals were to discover the complete set of human genes and make them accessible for further biological study, and determine the complete sequence of DNA bases in the human genome. See Timeline for more HGP history.

Human Genome News

Published from 1989 until 2002, this newsletter facilitated HGP communication, helped prevent duplication of research effort, and informed persons interested in genome research.