Archive Site Provided for Historical Purposes
Sponsored by the U.S. Department of Energy Human Genome Program
Human Genome News, March 1992; 3(6)
CHROMINFO, developed by Prakash Nadkarni and Stephen Reeders (Yale University), is a free computer program intended to serve as a liaison tool for researchers working on the same chromosome in different laboratories. This simple-to-use program, which is designed to record order, distance, and other information for loci on any chromosome, is menu driven and makes maximum use of the mouse. Users can edit information and add fields and text. The program was written for the Apple Macintosh (requires at least 3 Mb RAM) and works with the commercial database 4th Dimension (ACIUS). Yale University; Section of Nephrology; Department of Internal Medicine; School of Medicine; 2073 LMP; P.O. Box 3333; New Haven, CT 06510-8056; 203/785-7403; Internet: nadkarni@cs.yale.edu.
GeneID, an artificial intelligence system for analyzing vertebrate genomic DNA, predicts exons and gene structure. NetGene predicts human mRNA splice sites and associated coding regions and gives the confidence level for each prediction. A prototype (version 1.0) now provides access to both programs in a fast, automatic, e-mail response system, which is free to the research community. For information on accessing the system, send the message geneid info to geneid@darwin.bu.edu over Internet.
GeneID and NetGene have been tested thoroughly on sets of genes from GenBank® ; evaluations of these tests are available in NetGene (S. Brunak et al.) and in a computer file for Macintosh (Geneid.sit.hqx ) that can be obtained by including the line Preprint Request in the e-mail to geneid@darwin.bu.edu.
Users of MBCRR and BMERC national computer resources have online access from their accounts. For subscription information, contact Tom Graf at tom@mbcrr.harvard.edu. The following references contain more details on the systems: S. Brunak et al., J. Mol. Biol. 220, 49-65 (1991) and R. Guigo et al., J. Mol. Biol., in press (1992). Questions may be addressed to Steen Knudsen; University of West Florida; Bioinformatics Resource; University of West Florida; Gulf Breeze, FL 32561-3999; 904/934-2448, Fax: 904/934-9201; Internet: steen@darwin.bu.edu.
GenBank invites developers to add their products to the GenBank Software Clearinghouse database of molecular biology software available from vendors. To add sequence analysis programs or to obtain a copy of the clearinghouse, which is stored in relational database format, contact: Kate Yudin; GenBank c/o IntelliGenetics, Inc.; 700 E. El Camino Real; Mountain View, CA 94040; 415/962-7364; abe@genbank.bio.net.
HGMIS Staff
The electronic form of the newsletter may be cited in the following style:
Human Genome Program, U.S. Department of Energy, Human Genome News (v3n6).
The Human Genome Project (HGP) was an international 13-year effort, 1990 to 2003. Primary goals were to discover the complete set of human genes and make them accessible for further biological study, and determine the complete sequence of DNA bases in the human genome. See Timeline for more HGP history.
Published from 1989 until 2002, this newsletter facilitated HGP communication, helped prevent duplication of research effort, and informed persons interested in genome research.
