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Sponsored by the U.S. Department of Energy Human Genome Program

Human Genome News Archive Edition

Human Genome News, November 1992; 4(4)


Human Genome Program Newsgroup Facilitates Communication

The Human Genome Program Newsgroup, sponsored by the National Science Foundation and the NIH and DOE human genome programs, operates through the BIOSCI electronic bulletin board network to allow researchers worldwide to communicate, share ideas, and find solutions to problems. Genome-related information is distributed through the newsgroup, including requests for grant applications, reports from recent scientific and advisory meetings, announcements of future events, and listings of free software and services. Genome program staffs participate in the newsgroup and respond to postings when appropriate (address for posting messages: Nongenome researchers are encouraged to use this forum for discussing genome issues with the research community and funding agencies.

The BIOSCI network also supports about 30 other newsgroups of interest to biologists. For information on these newsgroups and BIOSCI, send a message to the Internet address (, which also serves BITNET users. For help in using these electronic addresses, contact Dave Kristofferson (415/962-7339 or

The Human Genome Program Newsgroup may also be accessed on USENET as bionet.molbio.genome-program. E-mail subscriptions are not needed by those who have access to USENET NEWS. All interested users are encouraged to obtain USENET NEWS software, which is in the public domain and more convenient than subscribing to newsgroups by e-mail.

BIOSCI Newsgroups: Partial Listing

    Arabidopsis genome project newsgroup
    Computer applications to biological databases
    Biological sciences software
    Chromosome 22 mapping and sequencing
    Mathematical and computer applications in biology
  • GDB:
    Messages to and from Genome Data Base staff
    Messages to and from GenBank staff
    Genetic linkage analysis newsgroup
    Molecular evolution research discussions
    Protein research discussions
    Scientific funding agency information

NCBI Repository of Molecular Biology Databases

NCBI maintains a repository over 20 molecular biology databases that are freely available for network users through Internet FTP. Some of the databases are listed below with their curators.

  • ACEDB: C. elegans Genomic Database (Richard Durbin and J. Thierry-Meig)
  • EcoSeq and EcoMap: Integrated E. coli Sequence and Map Data (Kenn Rudd)
  • EPD: Eukaryotic Promoter Database (Philipp Bucher)
  • FlyBase: Drosophila Genetic Database (Michael Ashburner)
  • KABAT: Sequences of Proteins of Immunological Interest (Elvin Kabat)
  • PROSITE: Dictionary of Protein Sites and Patterns (Amos Bairoch)
  • REBASE: Restriction Enzyme Database (Richard Roberts)
  • SWISS-PROT: Protein Sequence Database (Bairoch)
  • TFD: Database of Transcription Factors (David Ghosh)

A toolbox directory contains a set of software and data exchange specifications used by NCBI to produce portable software and includes ASN.1 tools and specifications for molecular sequence data. A pub directory offers public-domain software such as BLAST (a sequence-similarity search program) and MACAW (a multiple-sequence-alignment program).

All data in this repository can be transferred over Internet by FTP. To connect, users should type ftp or ftp and enter anonymous for the login name and their e-mail address as the password. Directories should be changed to repository, toolbox, or pub to download databases, ASN.1 tools, and public-domain software, respectively.

In addition to anonymous FTP access, NCBI is now distributing the May Data Repository CD-ROM at no charge on an experimental basis. The next release is scheduled for this month. A subscription service may be set up for future releases that occur at 6-month intervals, depending on demand and database update frequency. Questions, suggestions, requests for copies of the CD-ROM, and proposals for repository additions should be sent to Scott Federhen (301/496-2475, Fax: /480-9241, Internet:


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The electronic form of the newsletter may be cited in the following style:
Human Genome Program, U.S. Department of Energy, Human Genome News (v4n4).

Human Genome Project 1990–2003

The Human Genome Project (HGP) was an international 13-year effort, 1990 to 2003. Primary goals were to discover the complete set of human genes and make them accessible for further biological study, and determine the complete sequence of DNA bases in the human genome. See Timeline for more HGP history.

Human Genome News

Published from 1989 until 2002, this newsletter facilitated HGP communication, helped prevent duplication of research effort, and informed persons interested in genome research.