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Human Genome News Archive Edition

Human Genome News, March 1993; 4(6)


University of Iowa Cooperative Human Linkage Center

(NIH; established 1992)

Jeffrey C. Murray

Nancy Newkirk (319/335-6899, Fax: -6970)
Jeffrey Murray (-6946, Fax: -6970;
Cooperative Human Linkage Center
Department of Pediatrics
University of Iowa
Iowa City, IA 52242

Kenneth Buetow (Fox Chase Cancer Center), Geoffrey M. Duyk (Harvard University), James W. Hanson, Val C. Sheffield, James L. Weber (Marshfield Medical Research Foundation), Robert F. Weir


  • Expansion of the linkage map of the entire human genome to an average resolution of 2.5 cM based on high-heterozygosity STRP markers.
  • Evaluation of protection of human subjects and provision of training for social and behavioral scientists on issues of human and molecular genetics.


  • Development of pilot libraries highly enriched for STRPs.
  • Characterization of single-strand conformation and denaturing gradient gel electrophoresis polymorphisms in candidate genes for craniofacial and ocular disorders.
  • Preliminary incorporation of CEPH genotypes on new STRP microsatellite markers into preexisting multipoint linkage maps.
  • Construction of multipoint linkage maps using the CEPH database, version 5.0.


  • Laboratories at Marshfield Medical Research Foundation and University of Iowa available for genotyping to establish disease linkages or mutation detection searches for specific gene or genes, with CEPH maps and STRP resources.
  • Training opportunities with travel and stipend support available for secondary science teachers to develop comprehensive understanding of technology and social and ethical issues related to the Human Genome Project.

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The electronic form of the newsletter may be cited in the following style:
Human Genome Program, U.S. Department of Energy, Human Genome News (v4n6).

Human Genome Project 1990–2003

The Human Genome Project (HGP) was an international 13-year effort, 1990 to 2003. Primary goals were to discover the complete set of human genes and make them accessible for further biological study, and determine the complete sequence of DNA bases in the human genome. See Timeline for more HGP history.

Human Genome News

Published from 1989 until 2002, this newsletter facilitated HGP communication, helped prevent duplication of research effort, and informed persons interested in genome research.