Human Genome News, March 1993; 4(6)

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Human Genome News, March 1993; 4(6)

GENOME CENTER:

University of Texas Health Science Center at San Antonio

(NIH; established 1992)

DIRECTOR:
Susan L. Naylor

CONTACT:
Susan L. Naylor (512/567-3842, Fax: -6781)
University of Texas Health Science Center
Department of Cellular & Structural Biology
7703 Floyd Curl Drive
San Antonio, TX 78284-7762

OTHER KEY RESEARCHERS:
Robin Leach, Peter O'Connell, Stephanie Sherman (Emory University), Brad Windle

MAJOR GOALS:

Construction of radiation hybrid, genetic linkage, and contig maps for human chromosome 3.
Development of a chromosome 3-specific database (with the University of Utah genome center).

MAJOR ACCOMPLISHMENTS:

Production of framework hybrids that divide chromosome 3 into 21 regions.
Construction of 2 genetic linkage maps, one with 52 markers and another with 26 dinucleotide repeats, and a radiation hybrid map with 92 loci.
Isolation and assembly of 137 simple repeat polymorphisms for chromosome 3.
Design and assembly of PCR primers for 81 genes and 9 RFLPs.
Development of a semiautomated system for PCR reactions and an automated gel loader using robotics for both CEPH screening and analysis of radiation hybrids.

AVAILABLE RESOURCES:

Framework hybrids for chromosome 3.
PCR primers for polymorphic dinucleotide repeats and genes mapping to chromosome 3.
Scheme for automating CEPH typing.
Chromosome 3-specific database (in development with the University of Utah).
Pre- and postdoctoral training in human genome research.
CEPH YAC library (inserts, > 1 Mb).

Genome Centers Acronym List

HGMIS Staff

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The electronic form of the newsletter may be cited in the following style:
Human Genome Program, U.S. Department of Energy, Human Genome News (v4n6).

Human Genome Project 1990–2003

The Human Genome Project (HGP) was an international 13-year effort, 1990 to 2003. Primary goals were to discover the complete set of human genes and make them accessible for further biological study, and determine the complete sequence of DNA bases in the human genome. See Timeline for more HGP history.