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Human Genome News, May-June 1995; 7(1)
A new monochromosomal somatic cell hybrid panel from BIOS Laboratories consists of 24 distinct hybrids, of which 21 contain one and 3 contain two chromosomes. Most of the hybrids, developed and characterized by Raghbir Athwal (Temple University Medical School) in collaboration with BIOS, are constructed in the A9 mouse cell line, with four remaining in a Chinese hamster ovary background. The human donor genome is derived from the normal human fibroblast cell line GM0634. [BIOS Laboratories, Inc.; New Haven, Conn. (800/678-9487 or 203/773-1450, Fax: 800/315-7435)]
In collaboration with researchers led by Melvin Simon (California Institute of Technology), Research Genetics has constructed mouse and human genomic BAC libraries from which DNA pools, high-density membranes, and individual clones are now available. Library clones are arrayed in 384-well microtiter plates. For each library, large genomic DNA is prepared from cultured mouse 129/sv or human 978SK cell lines. Average insert size is 100 to 150 kb. [Research Genetics, Inc.; Huntsville, Ala. (800/533-4363, Fax: 205/536-9016, ResGen Products and Services have migrated to Invitrogen's website: http://mp.invitrogen.com/)]
DNA samples with characterized trinuclotide expansions are available from Huntington's disease and myotonic dystrophy patients and from fragile X syndrome patients and unaffected carriers. Printed catalog. [Human Genetic Mutant Cell Repository; Coriell Institute for Medical Research; Camden, N.J. 08103 (800/752-3805 or 609/757-4849, Fax: -9737)]
The electronic form of the newsletter may be cited in the following style:
Human Genome Program, U.S. Department of Energy, Human Genome News (v7n1).
The Human Genome Project (HGP) was an international 13-year effort, 1990 to 2003. Primary goals were to discover the complete set of human genes and make them accessible for further biological study, and determine the complete sequence of DNA bases in the human genome. See Timeline for more HGP history.