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Human Genome News, April-June 1996; 7(6)

GDB Links to Mammalian Homology, Enzyme Function Data

Genome Database (GDB) has reestablished links from over 1500 GDB human gene entries to mammalian homology data within the Mouse Genome Database (MGD) and to over 400 enzyme entries within the ENZYME database. Both types of links are accessible from gene entries in GDB.

Although its primary focus is the mouse, MGD's [http://www.informatics.jax.org/] homology data also includes gene symbols, chromosomal locations, and citations regarding numerous mammalian species. Mammalian homology data can be accessed from GDB by querying for a specific human gene (e.g., SOD1) and following the homology link to the relevant MGD entry.

ENZYME [http://www.expasy.org/enzyme/] database entries include the reaction catalyzed, cofactors, links to the PROSITE [http://us.expasy.org/prosite/] database (protein sites and patterns), and detailed SWISS-PROT [http://us.expasy.org/sprot/] entries. ENZYME database links are from protein products rather than from gene entries themselves. For example, the enzyme link for the human SOD1 gene can be found by querying for this gene, choosing "Protein SUPEROXIDE DISMUTASE" from the Gene SOD1 entry, and then selecting the "EC:" link.

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The electronic form of the newsletter may be cited in the following style:
Human Genome Program, U.S. Department of Energy, Human Genome News (v7n6).

Human Genome Project 1990–2003

The Human Genome Project (HGP) was an international 13-year effort, 1990 to 2003. Primary goals were to discover the complete set of human genes and make them accessible for further biological study, and determine the complete sequence of DNA bases in the human genome. See Timeline for more HGP history.

Human Genome News

Published from 1989 until 2002, this newsletter facilitated HGP communication, helped prevent duplication of research effort, and informed persons interested in genome research.