Sponsored by the U.S. Department of Energy Human Genome Program
Human Genome News Archive Edition
Human Genome News, Nov. 1994; 6(4):16
The second version of Mapping Panel #2 is available as cell cultures or DNA from the Human Genetic Mutant Cell Repository of the National Institute of General Medical Sciences (NIGMS). Version 2 consists of 24 human-rodent somatic cell hybrids, each retaining a single intact human chromosome. In the new monochromosomal hybrid for chromosome 1, GM/NA13139, 96% of the cells retain the human chromosome; in the new hybrid, GM/NA13140, 68% of the cells retain chromosome 20.
The panel has been characterized by the following tests, at minimum: (1) G-banded chromosome analysis, (2) in situ hybridization using biotinylated total human DNA, (3) Southern blot hybridization, and (4) analysis by the polymerase chain reaction.
For information or a repository catalog, contact the NIGMS Human Genetic Mutant Cell Repository; Coriell Cell Repositories; Coriell Institute for Medical Research; 401 Haddon Avenue; Camden, NJ 08103 (800/752-3805 or 609/757-4848, Fax: -9737).
The electronic form of the newsletter may be cited in the following style:
Human Genome Program, U.S. Department of Energy, Human Genome News (v6n4).
The Human Genome Project (HGP) was an international 13-year effort, 1990 to 2003. Primary goals were to discover the complete set of human genes and make them accessible for further biological study, and determine the complete sequence of DNA bases in the human genome. See Timeline for more HGP history.
Published from 1989 until 2002, this newsletter facilitated HGP communication, helped prevent duplication of research effort, and informed persons interested in genome research.