Human Genome Project Information. Click to return to home page.

Sponsored by the U.S. Department of Energy Human Genome Program

Human Genome News Archive Edition

Human Genome News, May 1991; 3(1)

Human/Rodent Somatic Cell Hybrid Mapping Panel Available from Coriell

The National Institute of General Medical Sciences (NIGMS) Human Genetic Mutant Cell Repository has Mapping Panel No. 1 DNA samples available for distribution. The panel consists of DNA isolated from 18 human/rodent somatic cell hybrids retaining from 1 to 19 human chromosomes. Fifteen samples were isolated from human/mouse somatic cell hybrids resulting from the fusion of male human fibroblasts (IMR-91) with the thymidine kinase-deficient mouse cell line (B-82). The panel is completed with DNA isolated from three monochromosomal hybrids retaining human chromosomes 9, 16, and X.

The panel has been characterized by the following:

  • G-banded chromosome analysis;
  • in situ hybridization analysis using biotinylated total human DNA to detect human chromosomes, human/rodent translocated chromosomes, and human chromosome fragments; and
  • Southern blot hybridization.

Probes were used for the short and long arms of all human chromosomes except 10, 13, 14, 15, 20, and 21, all of which were analyzed with long-arm probes only. The panel consists of 50 µg of DNA from each hybrid and 100 µg of DNA from each of three parental human and rodent cell lines.

Contact: Human Genetic Mutant Cell Repository; Coriell Institute for Medical Research; 401 Haddon Avenue; Camden, NJ 08103; [800/752-3805 in the United States; 609/757-4848 from other countries; Fax: 609/964-0254].


HGMIS Staff

Return to Table of Contents

The electronic form of the newsletter may be cited in the following style:
Human Genome Program, U.S. Department of Energy, Human Genome News (v3n1).

Human Genome Project 1990–2003

The Human Genome Project (HGP) was an international 13-year effort, 1990 to 2003. Primary goals were to discover the complete set of human genes and make them accessible for further biological study, and determine the complete sequence of DNA bases in the human genome. See Timeline for more HGP history.

Human Genome News

Published from 1989 until 2002, this newsletter facilitated HGP communication, helped prevent duplication of research effort, and informed persons interested in genome research.