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Human Genome News, September 1992; 4(3)

FlyBase: A Drosophila Relational Database

The NIH National Center for Human Genome Research (NCHGR) has awarded a 3-year grant for development of FlyBase, a relational database that will facilitate access to and handling of Drosophila information. The award is $610,390 for the first year.

Four project sites will help to establish and maintain the database, with each location undertaking specific curatorial functions. Sites, responsible investigators, and functions are listed below.

  • Harvard University (William Gelbart) will serve as programming center and maintain the master database, major programs, and tables relating to mobile genetic elements and genes introduced by germline transformations. These data tables will allow representation of up-to-date genetic and molecular maps of the fruit fly genome.
  • University of Cambridge (Michael Ashburner) will function as European database server site for FlyBase and maintain genetics tables.
  • Indiana University, Bloomington (Thomas Kaufman and Kathleen Matthews), will maintain tables of strains from the two funded U.S. Drosophila stock centers.
  • University of California, Los Angeles (John Merriam), will maintain tables relating to the molecular properties of genes.

"In the past, dedicated volunteers from the Drosophila genetics and molecular biology research community have maintained and distributed essential data resources for Drosophila genetics," says David Benton, NCHGR Program Administrator. "The rapid increase in the amount of available information now requires that a public database be established. This database will incorporate the wealth of information collected by Dan Lindsley and Michael Ashburner and others over many years and will be continuously updated with new research findings," he added.

Programs integrating FlyBase with DNA and protein sequence databases are being developed in collaboration with Carolyn Tolstoshev and James Ostell of the National Center for Biotechnology Information.

HGMIS Staff

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Human Genome Program, U.S. Department of Energy, Human Genome News (v4n3).

Human Genome Project 1990–2003

The Human Genome Project (HGP) was an international 13-year effort, 1990 to 2003. Primary goals were to discover the complete set of human genes and make them accessible for further biological study, and determine the complete sequence of DNA bases in the human genome. See Timeline for more HGP history.

Human Genome News

Published from 1989 until 2002, this newsletter facilitated HGP communication, helped prevent duplication of research effort, and informed persons interested in genome research.