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Human Genome News Archive Edition

Human Genome News, November 1992; 4(4)

GenBank Transition Provides Continuity

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On October 1 the NIH GenBank® Genetic Sequence Database, an international database of known DNA sequences, moved to the National Center for Biotechnology Information (NCBI) at the National Library of Medicine (NLM). GenBank contains over 100 million nucleotides, up from 40 million in 1991 and 1.5 million in 1985.

For the past 10 years, GenBank has been managed by the National Institute for General Medical Sciences (NIGMS), with database production and distribution contracted to Bolt, Baranek, and Newman from 1982 to 1987 and to IntelliGenetics, Inc. (IG) from 1987 to 1992. In 1988, Congress established NCBI to help create a national program for developing information systems for molecular biology. Over the past 2 years, NCBI has been working with NIGMS and IG to ensure a smooth transition.

GenBank data will continue to be compiled from direct submissions and journal scanning, including all journals previously scanned. In addition, specially trained biological indexers in the NLM Library Operations Division will identify and annotate nucleotide and protein sequences from more than 3600 journals in MEDLINE®, augmented by plant and veterinary science journals from the National Agricultural Library. Citations for sequence data are enhanced with abstracts from MEDLINE.

Authors should continue to submit data and Authorin material directly to Los Alamos National Laboratory (LANL) (Internet: gb-sub@genome.lanl.gov); under an interagency agreement, LANL processes, maintains, and releases submitted sequence data to NCBI. Other author submissions come from the DNA databases EMBL in Germany and DDBJ in Japan. To facilitate the submission of sequence data, the Authorin program for PC and Macintosh computers is available from IG (800/477-2459). Corrections and sequences missing from published data should be reported to update@ncbi.nlm.nih.gov.

NCBI-GenBank data is available on CD-ROM and through e-mail servers and FTP over the Internet (see Access to Genbank). The standard flat file format for GenBank data distribution will continue, in addition to an integrated database version that includes retrieval software on CD-ROM for text searching and browsing related bibliographic and sequence entries. See NCBI Repository of Molecular Biology Databases for more information.


Reported by Barbara Rapp
NCBI

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Human Genome Project 1990–2003

The Human Genome Project (HGP) was an international 13-year effort, 1990 to 2003. Primary goals were to discover the complete set of human genes and make them accessible for further biological study, and determine the complete sequence of DNA bases in the human genome. See Timeline for more HGP history.

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