Human Genome Project Information Archive

Archive Site Provided for Historical Purposes

Sponsored by the U.S. Department of Energy Human Genome Program

Human Genome News Archive Edition
go to list of issues »
Vol.10, No.3-4   October 1999 

In this issue...

Available in PDF

DOE '99 Oakland Highlights

Genome Project

In the News 

Microbial Genomics

Ethical, Legal, and Social Issues


Web, Other Resources, Publications


Meeting Calendars & Acronyms

  • Genome and Biotech Meeting 
  • Training Courses and Workshops 
  • Acronyms

HGN archives and subscriptions

Human Genome Project Information home

In the News

Human MHC Region Sequenced

Key to Transplant Rejection, Autoimmune Disease

Sequencing of the 4-Mb human Major Histocompatibility Complex (MHC) region of chromosome6 has been completed by the Sanger Centre, University of Washington, and Tokai University (http://www.sanger.ac.uk/HGP/Chr6/MHC.shtml).

Proteins encoded by genes residing in the MHC region are responsible for helping the body defend itself against microscopic invaders by distinguishing normal body constituents ("self") from everything else, which it then marks for extinction. Researchers hope that a better understanding of MHC proteins will lead to the development of new ways to minimize transplant rejection and fight such infectious and autoimmune diseases as arthritis and juvenile diabetes.

The electronic form of the newsletter may be cited in the following style:
Human Genome Program, U.S. Department of Energy, Human Genome News (v10n3-4).

Human Genome Project 1990–2003

The Human Genome Project (HGP) was an international 13-year effort, 1990 to 2003. Primary goals were to discover the complete set of human genes and make them accessible for further biological study, and determine the complete sequence of DNA bases in the human genome. See Timeline for more HGP history.

Human Genome News

Published from 1989 until 2002, this newsletter facilitated HGP communication, helped prevent duplication of research effort, and informed persons interested in genome research.