Sponsored by the U.S. Department of Energy Human Genome Program
Human Genome News Archive Edition
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In the News
Web, Publications, Resources
Meeting Calendars & Acronyms
Breast Cancer Researchers Use Gene Expressions
Using gene-expression profiling, an international group of researchers led by Jeffrey Trent (NIH National Human Genome Research Institute) has made it possible to distinguish between hereditary and sporadic breast tumors for the first time. Simultaneous microarray assessments of some 6000 genes within breast cancer cells revealed clear and unique differences in activity patterns, leading to a new test that shows exactly which genes are active in a tumor cell. This capability may have important implications for both diagnosis and treatment. The findings were published in the New England Journal of Medicine 344(8), 539 48 (February 22, 2001).
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The Human Genome Project (HGP) was an international 13-year effort, 1990 to 2003. Primary goals were to discover the complete set of human genes and make them accessible for further biological study, and determine the complete sequence of DNA bases in the human genome. See Timeline for more HGP history.
Published from 1989 until 2002, this newsletter facilitated HGP communication, helped prevent duplication of research effort, and informed persons interested in genome research.