Archive Site Provided for Historical Purposes
Sponsored by the U.S. Department of Energy Human Genome Program
In this issue...
In the News
Special Meeting Report
Web, Publications, Resources
Funding Information
Meeting Calendars & Acronyms
Proceedings from all DOE Human Genome Program contractor-grantee workshops, including this years Oakland meeting, are on the Web: www.ornl.gov/hgmis/publicat/index.shtml
The 2002 proceedings also contain abstracts of DOEs Microbial Genome and Low Dose Radiation Research programs.
A Beryllium Symposium will be held June 2526 at the National Library of Medicine in Bethesda, Maryland (www.ornl.gov/meetings/beryllium/). It is sponsored by DOE in cooperation with the National Jewish Medical and Research Center and the Centers for Disease Control and Preventions National Institute for Occupational Safety and Health.
Abstracts from the second meeting on Exceptional Chromosome Regions (ECR2), along with abstracts and references from ECR1, are at www.ornl.gov/meetings/ecr2.pdf. ECR2 was held in Oakland, California, in May 2001 to continue consideration of special resources and technologies for clarifying chromosome structure and DNA sequence in particularly difficult regions, including near telomeres and centromeres and at large duplications.
The Protein Data Bank Annual Report: July 2000June 2001 is on the Web (www.rcsb.org/pdb/annual_report01.pdf). It contains information on the purpose, mission, and history of PDB; data distribution and access; outreach and education; administration; progress and achievements; collaborations with other organizations; future of PDB; and selected references.
A meeting report and abstracts from the 11th annual Beyond the Identification of Transcribed Sequences: Functional and Expression Analysis workshop held November 912, 2001, in Washington, D.C., are on the Web (www.ornl.gov/meetings/bits2001.pdf).
The NABIR Strategic Plan (2001) is on the Web (www.lbl.gov/nabir/researchprogram/strategicplan/NABIR_strat_plan.pdf). [Note: Site no longer active; visit http://doesbr.org/] The Natural and Accelerated Bioremediation Research program focuses on radionuclides and metals that are of great concern at DOE sites and are tractable through bioremediation. The current NABIR program announcement is at www.er.doe.gov/production/grants/LAB02_12.html.
Program Notice 02-13
www.sc.doe.gov/production/grants/fr02-13.html
The DOE Office of Biological and Environmental Research and the Office of Advanced Scientific Computing Research have issued an RFA for large multidisciplinary teams to support the Genomes to Life program (genomicsgtl.energy.gov). A central theme of GTL is to develop capabilities for predicting the behavior of microbes and microbial communities of interest to DOE (see Genomes to Life Program Funded for FY 2002 for more details).
Applications due: May 7
Contacts: david.thomassen@science.doe.gov, 301/903-9817 and walt.polansky@science.doe.gov, 301/903-5800
A complementary request for proposals from teams led by DOE national laboratories was issued earlier (www.sc.doe.gov/production/grants/LAB02_13.html).
DOE is seeking nominations for candidate microbes and microbial communities to sequence in support of the Microbial Genome and Genomes to Life programs (http://microbialgenomics.energy.gov/funding/seqtargets.shtml). Candidate microbes should be relevant to DOE missions including waste remediation, carbon management, energy production, and biodefense. Sequencing will be carried out at the DOE Production Genomics Facility of the Joint Genome Institute (www.jgi.doe.gov).
Nominations are due March 28, and review will be completed early in the summer. Draft sequencing will begin later in the year after high-quality DNA has been provided.
The NIH National Human Genome Research Institute (NHGRI) has developed a new competitive process for selecting genomes to be sequenced with NHGRI support. Based on the submission and review of white papers, the new procedure will apply to all organisms except eubacteria, archaea, and plants, which are more appropriate to the missions of other NIH components or other agencies.
White papers will be accepted three times a year: February 10, June10, and October 10.
Ethical, Legal, and Social Implications
Program Notice 02-14
www.er.doe.gov/production/grants/fr02-14.html
Topic: Issues of genetics and the workplace, storage of genetic information and tissue samples, education, and complex or multigenic traits.
Applications due: March 28
Contact: daniel.drell@science.doe.gov, 301/903-6488
Latest ELSI awards: www.ornl.gov/hgmis/resource/elsi2001.shtml
Mouse Genome Monthly, being produced for several months by the Mouse Sequencing Liaison Group, is designed to keep the research community abreast of sequencing progress. The newsletter and related information are available on the Web (www.nih.gov/science/models/mouse/genomics/).
The electronic form of the newsletter may be cited in the following style:
Human Genome Program, U.S. Department of Energy, Human Genome News (v12n1-2).
The Human Genome Project (HGP) was an international 13-year effort, 1990 to 2003. Primary goals were to discover the complete set of human genes and make them accessible for further biological study, and determine the complete sequence of DNA bases in the human genome. See Timeline for more HGP history.
Published from 1989 until 2002, this newsletter facilitated HGP communication, helped prevent duplication of research effort, and informed persons interested in genome research.