Sponsored by the U.S. Department of Energy Human Genome Program
Human Genome News Archive Edition
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In the News
Ethical, Legal, and Social Issues and Educational Resources
Genetics in Medicine
Web, Other Resources, Publications
Meeting Calendars & Acronyms
Mouse Consortium for Functional Genomics
Six Tennessee research organizations located from Memphis to Knoxville signed a Memorandum of Cooperation on December 4, 1998, to form the Tennessee Mouse Consortium for Functional Genomics. The consortium's purpose is to induce gene mutations in mice as models for human genetic diseases and as subjects for studying gene function. Consortium members are Oak Ridge National Laboratory (ORNL), University of Tennessee (Knoxville and Memphis), Vanderbilt University Medical Center, Meharry Medical College, and St. Jude Children's Research Hospital. The collaboration will combine ORNL's experience in mouse genetics and functional genomics with the other institutions' biological and clinical expertise. Vanderbilt, for example, will contribute proficiency in behavioral neurosciences, while Meharry is especially interested in mutations in the sensory systems. Each institution will play a crucial role in screening mutagenized mice for induced changes in behavior, physiology, biochemistry, and morphology and will choose mutations of interest for detailed study.
The ORNL Laboratory for Comparative and Functional Genomics, with its large collection of mutant mouse stocks and large-scale mutagenesis and phenotype screening program, is the center facility of the consortium. The six sites will be linked by the Internet, and the consortium will be managed by Darla Miller at ORNL.
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The Human Genome Project (HGP) was an international 13-year effort, 1990 to 2003. Primary goals were to discover the complete set of human genes and make them accessible for further biological study, and determine the complete sequence of DNA bases in the human genome. See Timeline for more HGP history.
Published from 1989 until 2002, this newsletter facilitated HGP communication, helped prevent duplication of research effort, and informed persons interested in genome research.