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In the special genome issue of Science (October 23, 1998), researchers reported the release of GeneMap 98, an updated human gene map that provides an early look at some of the most important regions of the human genome. Two to three times more detailed than the 1996 version, the new map contains some 30,000 human gene-based markers. It doubles the gene density of the previous release and represents perhaps half of all human genes.
The map highlights important chromosomal landmarks that (1) provide a valuable resource for studying complex (polygenic) genetic traits and (2) offer a framework and focus for constructing complete physical maps of chromosomes for genome sequencing. An important tool for aiding design and construction of large-scale gene-expression arrays, the map also can be used to study comparative analysis of mammalian chromosome structure and evolution. GeneMap 98 is available on a redesigned Web site [http://www.ncbi.nlm.nih.gov/genemap99/] that includes mapping information and associated data and annotations.
The electronic form of the newsletter may be cited in the following style:
Human Genome Program, U.S. Department of Energy, Human Genome News (v10n1-2).
The Human Genome Project (HGP) was an international 13-year effort, 1990 to 2003. Primary goals were to discover the complete set of human genes and make them accessible for further biological study, and determine the complete sequence of DNA bases in the human genome. See Timeline for more HGP history.