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Sponsored by the U.S. Department of Energy Human Genome Program

Human Genome News Archive Edition
  Vol.10, No.1-2   February 1999
Available in PDF 
In this issue... 

Genome Project 

In the News 

Microbial Genomics 

Ethical, Legal, and Social Issues and Educational Resources 


Genetics in Medicine 


Web, Other Resources, Publications 


Meeting Calendars & Acronyms 

  • Genome and Biotechnology Meetings 
  • Training Courses and Workshops 
  • Acronyms 

HGN archives and subscriptions 
HGP Information home

Software Programs Provide Useful Resources


BioToolKit now provides 750 annotated links to Web tools for the study of nucleic acid, genome, and protein structure.

Gene-Finding Programs at Sanger

Updated versions of gene-finding programs (including FGENES, FGENESH, and FGENES-m variant for mammalian sequences) are available for use through the Sanger Web site. Also, the Gapped BLASTP program from the National Center for Biotechnology Information allows users to check a gene's protein structure in the INFOGENEP database of finished and unfinished human sequences and receive the clone's name and sequence. See the Web site for more information.

New Sequin Version

The National Center for Biotechnology Information has released Version 2.80 of Sequin, the sequence-submission and editing tool, for all platforms. This version is expected to be particularly useful for genome centers that annotate large records.

Tandem Repeat Tool

Gary Benson (Mount Sinai School of Medicine) has developed a program to find tandem repeats in DNA sequence data without prior knowledge of pattern repeat, pattern size, or number of copies. The current version finds pattern repeats ranging from 1 to 500 bases.

Users submitting a sequence (up to 2 Mb) in FASTA format will receive a summary table of repeats, including their location, size, number of copies, and nucleotide content. Clicking on an entry shows alignment against a consensus pattern, allowing the user to see the repeat pattern and mutation location.

Sequence Viewer

Sequence Viewer, a free public software tool for viewing and analyzing DNA sequences, is available on the National Center for Genome Resources (NCGR) Web site. The NCGR tool was developed to fill the need for graphical representations of nucleotide sequences in the Genome Sequence DataBase and for detailed descriptions of sequence annotation. Sequence Viewer allows users to quickly find a sequence region that integrates with a gene rather than searching through a lengthy, complex flat-file report. It also can be used as a quality-control tool for readily locating mistakes in feature position.

The electronic form of the newsletter may be cited in the following style:
Human Genome Program, U.S. Department of Energy, Human Genome News (v10n1-2).

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Acronym List

Human Genome Project 1990–2003

The Human Genome Project (HGP) was an international 13-year effort, 1990 to 2003. Primary goals were to discover the complete set of human genes and make them accessible for further biological study, and determine the complete sequence of DNA bases in the human genome. See Timeline for more HGP history.

Human Genome News

Published from 1989 until 2002, this newsletter facilitated HGP communication, helped prevent duplication of research effort, and informed persons interested in genome research.